Researchers in the UK say they’ve developed the first reliable blood test to detect myalgic encephalomyelitis, or chronic fatigue syndrome (ME/CFS).
The team from the University of East Anglia and Oxford Biodynamics found unique DNA-folding patterns in ME/CFS patients’ blood.
Testing 47 patients and 61 healthy volunteers, they achieved 92% sensitivity and 98% specificity — a major diagnostic breakthrough.
“This is a significant step forward,” said lead researcher Prof Dmitry Pshezhetskiy. “It could transform how we diagnose and manage ME/CFS.”
The test uses epigenetic markers, which can change during life, to identify disease signatures more accurately than genetic testing.
However, some experts urged caution, calling for wider validation before clinical use.
“These results are promising but need confirmation in larger, independent studies,” said Dr Charles Shepherd of the ME Association.
Prof Chris Ponting warned claims were “premature,” adding the test could cost around £1,000 per patient.
