The first global systematic review has found that receiving the shingles vaccine is associated with an 18% lower risk of stroke or heart attack in adults. Researchers analyzed data from 19 studies, including both observational research and randomized controlled trials, and found cardiovascular benefits in adults aged 18 and older, with a 16% risk reduction specifically in those over 50.
Shingles, caused by the reactivation of the herpes zoster virus, can lead to painful rashes and serious complications, especially in older adults. The study suggests that vaccination may reduce systemic inflammation triggered by shingles, which could help protect the heart and circulatory system.
Experts caution that while the findings are promising, more research is needed to confirm causality and understand the mechanisms behind the effect. Health authorities, including the NHS, are expanding vaccine eligibility to younger adults with weakened immune systems, potentially increasing protection against both shingles and cardiovascular events.
